How fine is it to crush traditional Chinese medicine

We are a professional research, design, production, sales of ultra-fine grinding, cell wall breaking equipment manufacturers, who need to use ultra-fine powder, cell wall breaking, will be our potential customers, so we know many friends from all over the world.

Many customers call to ask a question: how detailed can your device do, or how many items can you do? My usual response is: how detailed do you need to be, or how many items do you need to be? The answer of many customers is: the more detailed, the better. Here comes the problem. In fact, the fineness of the materials we make depends on the type of materials and the requirements for the products. To put it simply: your product can meet the requirements if it reaches 200 mesh. Is it necessary for you to achieve 500 mesh or more? There is also the problem of comminution cost, and then the method and technical requirements of powder detection.

Let's take traditional Chinese medicine as an example. In the Chinese Pharmacopoeia, 200 mesh is already fine powder. If we make the traditional Chinese medicine nanometer level, what will be the problem? Can traditional Chinese medicine be modified? Will it change from tonic to poison? This is a very serious problem. We need to make great efforts to study it. If we are not sure about this issue, let's not mention it first. The more detailed the better. The concept we put forward is: cell level ultrafine comminution, that is, traditional Chinese medicine can break cell wall (membrane). After the plant cell wall or animal cell membrane is broken, the effective components are fully dissolved, which can effectively improve the dissolution, significantly enhance the efficacy of traditional Chinese medicine, make the human body fully absorb, reduce the use and consumption of medicinal materials, reduce the cost of medicinal materials, and significantly improve the economic benefits.

So how thin do you need to be to break the cell wall? We think that it is enough to achieve - 300 mesh (the central particle size is 4-15 μ m under the electron microscope).

The cell scale of traditional Chinese medicine (plant and animal medicine) is generally about 10um-100um. After the superfine powder produced by fengxu Machinery Technology Co., Ltd., the superfine powder of traditional Chinese medicine can reach - 300 mesh sieve (the inner diameter of 300 mesh sieve is 47um), its particle size distribution is about 50% in 12-15um, and the upper limit size is ＜ 47um, which is twice smaller than the upper limit size of 200 mesh 75um95% and 150 mesh (90um) 100% specified in Chinese pharmacopoeia in 2000. Analysis shows that: after 300 mesh, the comprehensive cell wall breaking rate can reach more than 90%. After cell wall breaking, traditional Chinese medicine has the following characteristics

1、 Improve bioavailability. After the cell wall (membrane) is broken, the contents of the cell can be in direct contact with the solvent, the active ingredients can all enter the solvent and be absorbed by the human body, the onset time of the drug will be significantly shortened, the action time of the drug on the human body will be shorter, and the action intensity will be higher.

2、 The full homogenization in comminution of compound Chinese medicine. Many traditional Chinese medicines are compound, and many kinds of compound are crushed. The effective ingredients can be fully and evenly mixed, and various ingredients can be evenly absorbed by the human body, which can also enhance the effect of drugs. Therefore, our equipment has another very important function: mixing (precision compounding).

3、 Improve the industrial extraction rate of effective components. After the cell wall (membrane) was broken, the resistance of cell dissolution was reduced, so the extraction rate was significantly increased.

4、 Sterilization. After the cell wall is broken, the insect eggs in the medicinal materials will also be killed, reducing the threat of insect pests to the Chinese medicinal materials.

In conclusion, the superfine comminution of traditional Chinese medicine should not simply pursue fineness. Practice has proved that: Jinan fengxu Machinery Technology Co., Ltd. produced a series of cell level ultra-fine grinding equipment, for thousands of varieties of traditional Chinese medicine, can easily achieve 300 mesh cell wall breaking. Is it necessary for our customers to pursue 1000 items or even 3000 items? Some friends reflect that other manufacturers claim to do thousands of samples, the test results are not as good as we do 300 samples. Obviously, the fineness of the powder is distributed. Among them, the proportion of 10um, 20um, 50um, 70UM or 100um needs professional detection methods. Airflow mill can be classified, so the powder may be finer, but airflow mill has limitations for some Chinese medicinal materials. For example: 1, strong fiber materials (Ganoderma lucidum, licorice, astragalus, eucommia, etc.); 2. Strong and tough materials (seahorse, tortoiseshell, sea cucumber, etc.); 3. High sugar materials (wolfberry, jujube, etc.); 4. Sticky materials (raw land, cooked land, Ophiopogon japonicus, etc.); 5. Resin materials (frankincense, plaster, etc.); 6. Volatile materials (borneol, musk, etc.); Spore materials (Ganoderma lucidum spore powder, pine pollen, etc.) and so on, there is no way for these varieties of materials to be crushed by air flow. Therefore, the choice of crushing equipment mainly depends on the product variety, material characteristics and crushing requirements. In a word, we should be clear about what we are going to do and what our goals and requirements are! In the case of meeting the requirements of crushing fineness, it is necessary to reduce the loss as far as possible, reduce the loss of effective ingredients, and reduce the crushing cost. It also depends on the complexity of equipment operation, floor area, power consumption, manpower, efficiency, output, etc!

The above is just a simple talk about the situation of traditional Chinese medicine crushing. In fact, there are a lot of comminution applications, such as health care products, cosmetics, chemical products, building materials, electronics, military industry and so on. Seeing is believing, hearing is believing. If you are interested, you can send some samples to our company. For samples within 500g, we can provide free tests. It's not too late for you to take back and draw a conclusion. We also welcome friends from all walks of life to visit our company. We hope our products can create more value and higher benefits for more customers.